Are you confused about the ICD-10 codes related to anemia? Don't worry, you're not alone. Understanding these codes is crucial for accurate diagnosis, and it can significantly impact patient care. In this article, we will decode the ICD-10 codes for anemia and shed light on their importance in the healthcare industry.
icd 10 Codes, Treatment of Anemia, Symptoms of Anemia, anemia signs, aplastic anemia

Table of Contents

Anemia happens when you do not have enough red blood cells. The cells travel with iron and hemoglobin, which is a protein that helps carry oxygen through the bloodstream to your organs all through the body.

Whether you’re a healthcare professional or a patient seeking clarity, this article will help you to understand anemia ICD-10 codes and empower you to navigate the world of medical diagnosis with confidence. Let’s dive in and decode the language of anemia.

What is anemia?

Anemia is a medical condition characterized by a decrease in the number of red blood cells or a decrease in the amount of hemoglobin in the blood. Hemoglobin is the protein responsible for carrying oxygen to the body’s tissues. When the body lacks sufficient red blood cells or hemoglobin, it can lead to various symptoms and health complications.

There are several types of anemia, including iron deficiency anemia, vitamin deficiency anemia, hemolytic anemia, and sickle cell anemia, among others. Each type of anemia has its own unique causes and symptoms, and accurate diagnosis is essential for effective treatment.

Anemia can result from various factors, including nutritional deficiencies, chronic diseases, genetic disorders, and medication side effects. It can also be a symptom of an underlying health condition, such as kidney disease, cancer, or autoimmune disorders. Understanding the underlying causes is crucial for proper diagnosis and management.

Common causes of anemia

When someone develops anemia, they are said to be “anemic.” Being anemic might mean that you feel more tired or cold than you usually do, or if your skin seems too pale. This is due to your organs not receiving the oxygen they need to do their jobs. The most common types of anemia are aplastic anemia, iron deficiency anemia, sickle cell anemia, thalassemia, and vitamin deficiency anemia.

Anemia can be caused by a variety of factors, including nutritional deficiencies, chronic diseases, genetic disorders, and medication side effects. Let’s explore some of the common causes in more detail:

1 Fatigue and weakness :

This is the most common cause of anemia worldwide. Iron is essential for the production of hemoglobin, and a deficiency can lead to decreased red blood cell production. Iron deficiency can result from inadequate dietary intake, poor absorption, or increased iron requirements during pregnancy or growth.

2Vitamin deficiency :

Deficiencies in vitamins such as vitamin B12 and folate can impair red blood cell production and lead to anemia. These vitamins are necessary for the synthesis of DNA, which is required for red blood cell formation. Poor dietary intake, malabsorption, or certain medical conditions can contribute to vitamin deficiencies.

3Chronic diseases :

Chronic diseases, such as kidney disease, cancer, and autoimmune disorders, can cause anemia by interfering with the body’s ability to produce or maintain healthy red blood cells. Inflammatory processes, hormonal imbalances, and reduced kidney function can all contribute to anemia in these cases.

4Genetic disorders :

Certain genetic disorders, such as sickle cell anemia and thalassemia, can result in abnormal red blood cell production or function. These disorders are typically inherited and can cause chronic anemia and other complications throughout a person’s life.

5Medication side effects :

Some medications, such as chemotherapy drugs, can cause bone marrow suppression, leading to a decrease in red blood cell production. Other medications, like nonsteroidal anti-inflammatory drugs (NSAIDs), can cause gastrointestinal bleeding, which can result in iron deficiency anemia.

It’s important to identify the underlying cause of anemia to ensure appropriate treatment and management. Accurate diagnosis is key, and this is where the ICD-10 codes play a crucial role.


Anemia signs and symptoms vary depending on the cause. If the anemia is caused by a chronic disease, the disease can mask them, so that the anemia might be detected by tests for another condition. Depending on the causes of your anemia, you might have no symptoms. Signs and symptoms, if they do occur, might include fatigue, weakness, pale or yellowish skin, irregular heartbeats, shortness of breath, dizziness or lightheadedness, chest pain, cold hands and feet, and headaches.

1 Fatigue and weakness :

Feeling tired and lacking energy are common symptoms of anemia. This is due to the reduced oxygen-carrying capacity of the blood, which can result in decreased energy production in the body

2Shortness of breath :

Anemia can cause the body to compensate by increasing heart rate and respiratory rate to deliver more oxygen to the tissues. This can lead to shortness of breath, especially during physical activity or exertion.

3Pale skin and mucous membranes :

Anemia can cause a decrease in the number of red blood cells, resulting in reduced blood flow to the skin and mucous membranes. This can lead to a pale or yellowish appearance.

4Dizziness and lightheadedness :

Insufficient oxygen supply to the brain can cause dizziness and lightheadedness. These symptoms may be more pronounced when standing up or exerting oneself.

5 Rapid or irregular heartbeat :

Anemia can lead to an increased heart rate as the body tries to compensate for the reduced oxygen-carrying capacity of the blood. This can result in a rapid or irregular heartbeat.

It’s important to note that these symptoms can vary depending on the severity of anemia and the individual’s overall health. If you’re experiencing any of these symptoms, it’s crucial to consult a healthcare professional for proper diagnosis and treatment.


Anemia treatment depends on the cause. Treatment for iron deficiency anemia usually involves taking iron supplements and changing your diet. Treatment for folic acid and vitamin C deficiency involves dietary supplements and increasing these nutrients in your diet. Treatment for aplastic anemia can include blood transfusions to boost levels of red blood cells. Treatment for sickle cell anemia might include oxygen, pain relievers, and oral and intravenous fluids to reduce pain and prevent complications. Most forms of thalassemia are mild and require no treatment.

ICD-10 codes for anemia

ICD-10 codes provide a detailed classification system for different types of anemia. These codes help healthcare professionals differentiate between the various causes and severity of anemia, allowing for more accurate diagnosis, treatment, and tracking of the condition. Let’s explore some of the commonly used ICD-10 codes for anemia:

ICD-10 ChapterCodesCode Description
3D50.0 Iron deficiency anemia secondary to blood loss (chronic)
3D50.1Sideropenic dysphagia
3D50.8Other iron deficiency anemias
3D50.9Iron deficiency anemia, unspecified
3D51.0Vitamin B12 deficiency anemia due to intrinsic factor deficiency
3D51.1Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria
3D51.2Transcobalamin II deficiency
3D51.3Other dietary vitamin B12 deficiency anemia
3D51.8Other vitamin B12 deficiency anemias
3D51.9Vitamin B12 deficiency anemia, unspecified
3D52.0Dietary folate deficiency anemia
3D52.1Drug-induced folate deficiency anemia
3D52.8Other folate deficiency anemias
3D52.9Folate deficiency anemia, unspecified
3D53.0Protein deficiency anemia
3D53.1Other megaloblastic anemias, not elsewhere classified
3D53.2Scorbutic anemia
3D53.8Other specified nutritional anemias
3D53.9Nutritional anemia, unspecified
3D55.0Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
3D55.1Anemia due to other disorders of glutathione metabolism
3D55.2Anemia due to disorders of glycolytic enzymes
3D55.3Anemia due to disorders of nucleotide metabolism
3D55.8Other anemias due to enzyme disorders
3D55.9Anemia due to enzyme disorder, unspecified
3D56.0Alpha thalassemia
3D56.1Beta thalassemia
3D56.2Delta-beta thalassemia
3D56.3Thalassemia minor
3D56.4Hereditary persistence of fetal hemoglobin [HPFH]
3D56.5Hemoglobin E-beta thalassemia
3D56.8Other thalassemias
3D56.9Thalassemia, unspecified
3D57.00Hb-SS disease with crisis unspecified
3D57.01Hb-SS disease with acute chest syndrome
3D57.02Hb-SS disease with splenic sequestration
3D57.1Sickle-cell disease without crisis
3D57.20Sickle-cell/Hb-C disease without crisis
3D57.211Sickle-cell/Hb-C disease with acute chest syndrome
3D57.212Sickle-cell/Hb-C disease with splenic sequestration
3D57.219Sickle-cell/Hb-C disease with crisis, unspecified
3D57.3Sickle-cell trait
3D57.40Sickle-cell thalassemia, without crisis
3D57.411Sickle-cell thalassemia with acute chest syndrome
3D57.412Sickle-cell thalassemia with splenic sequestration
3D57.419Sickle-cell thalassemia with crisis unspecified
3D57.80Other sickle-cell disorders, without crisis
3D57.811Other sickle-cell disorders with acute chest syndrome
3D57.812Other sickle-cell disorders with splenic sequestration
3D57.819Other sickle-cell disorders with crisis, unspecified
3D58.0Hereditary spherocytosis
3D58.1Hereditary elliptocytosis
3D58.2Other hemoglobinopathies
3D58.8Other specified hereditary hemolytic anemias
3D58.9Hereditary hemolytic anemia, unspecified
3D59.0Drug-induced autoimmune hemolytic anemia
3D59.1Other autoimmune hemolytic anemias
3D59.2Drug-induced nonautoimmune hemolytic anemia
3D59.3Hemolytic-uremic syndrome
3D59.4Other nonautoimmune hemolytic anemias
3D59.5Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
3D59.6Hemoglobinuria due to hemolysis from other external causes
3D59.8Other acquired hemolytic anemias
3D59.9Acquired hemolytic anemia, unspecified
3D60.0Chronic acquired pure red cell aplasia
3D60.1Transient acquired pure red cell aplasia
3D60.8Other acquired pure red cell aplasias
3D60.9Acquired pure red cell aplasia, unspecified
3D61.01Constitutional (pure) red blood cell aplasia
3D61.09Other constitutional aplastic anemia
3D61.1Drug-induced aplastic anemia
3D61.2Aplastic anemia due to other external agents
3D61.3Idiopathic aplastic anemia
3D61.810Antineoplastic chemotherapy induced pancytopenia
3D61.811Other drug-induced pancytopenia
3D61.818Other pancytopenia
3D61.89Other specified aplastic anemias and other bone marrow failure syndromes
3D61.9Aplastic anemia, unspecified
3D62Acute posthemorrhagic anemia
3D63.0Anemia in neoplastic disease
3D63.1Anemia in chronic kidney disease
3D63.8Anemia in other chronic diseases classified elsewhere
3D64.0Hereditary sideroblastic anemia
3D64.1Secondary sideroblastic anemia due to disease
3D64.2Secondary sideroblastic anemia due to drugs and toxins
3D64.3Other sideroblastic anemias
3D64.4Congenital dyserythropoietic anemia
3D64.81Anemia due to antineoplastic chemotherapy
3D64.89Other specified anemias
3D64.9Anemia, unspecified

These are just a few examples of the ICD-10 codes related to anemia. Each code provides specific information about the type, cause, and severity of the anemia, allowing healthcare professionals to accurately document and communicate the diagnosis.

The role of ICD-10 codes in improving anemia diagnosis

Accurate diagnosis is crucial for effective management and treatment of anemia. ICD-10 codes provide a standardized classification system that enables healthcare professionals to document and communicate anemia diagnoses accurately. By understanding and utilizing these codes, healthcare providers can enhance their diagnosis accuracy, improve patient management, and ensure appropriate treatment plans.

From iron deficiency anemia to hemolytic anemias and other blood disorders, the ICD-10 codes provide a comprehensive framework for anemia diagnosis. By accurately documenting the type, cause, and severity of anemia, healthcare professionals can develop tailored treatment plans, monitor patient progress, and improve health outcomes.

Whether you’re a healthcare professional or a patient seeking clarity, understanding the ICD-10 codes related to anemia is essential. It empowers you to navigate the world of medical diagnosis with confidence and ensures that you receive the appropriate care and treatment for your condition.
Remember, accurate diagnosis starts with understanding the language of anemia. With the help of ICD-10 codes, healthcare professionals can decode the complexities of anemia and provide better care for their patients.

Author: Tonoya Ahmed

DocCharge Logo

About DocCharge

DocCharge: Be productive again! Practice analytics, mobile charge capture, HIPAA compliant messaging, and tools for billers.
DocCharge is a mobile physician productivity platform enabling physicians and clinicians to save time by efficiently capture patient billings, communicate with back office and maximize revenue by avoiding lost charges using real-time analytics on a mobile device. Designed by a physician for fellow physicians, residents/fellows, and mid-level providers, DocCharge maximizes one’s productivity. Practice Administrators and outsourced billing companies find the application very intuitive, thus improving practice efficiency and revenue.
DocCharge is transforming healthcare data into useful and actionable insights, thereby allowing partner subscribers to focus their resources on the core business of providing high quality patient care. For more information, visit, email:

Be Productive Again with DocCharge Resources

Join our fellow professionals! Be in touch with the latest medical news directly in your Inbox. Enter your email address below: